The Latin and French antecedents of the Spanish lives of St. Mary Magdalene and St Martha in ms Escorial h.I 13.

PhDThe Spanish Magdalene and Martha lives in MS Escorial h. I. 13 are translations of Old French texts represented by MSS C and F respectively, and not of any other Latin or French source. The C French and D Franco-Provençal versions of the Magdalene life are independent translations of the Latin B text, and the F and C5 French versions of the Martha life are independently executed versions of the Latin E text. There are, however, some puzzling affinities between the Latin and Spanish texts. The shorter Latin Magdalene life A. is the original version, which was elaborated to form the longer Latin life B. The C French translation is shorter than B. but its source is the longer B rather than the shorter A. text, the differences between original and translation being explained by the adaptive translation process. Comparison between the more complete D translation and the simplifying C text shows that the two versions C and D were intended for very different uses. The two-French Martha translations, F and C5 are from Latin originals much closer to the E Latin text than to the Sanctuarium. F is a simplifying translation, intended, like the C Magdalene text, for oral delivery, while, C5 is a more complete rendering, intended for private reading by aristocratic ladies. The Spanish MS could not have contained complete, translations of both the Magdalene and the Martha lives, since the missing, four folios would not have been sufficient for the material involved. The distribution of non-standard linguistic features shows that the two Spanish texts are the work of two different translators. The Spanish translations are both, in general, accurately and competently executed, but the differing numbers of errors, additions, omissions and changes in each confirms that they are the work of two different translators

Mapping the wind in the polar thermosphere a case study within the CEDAR Program

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/95064/1/eost7749.pd

In Vivo Assessment of Arsenic Bioavailability in Rice and Its Significance for Human Health Risk Assessment

BACKGROUND: Millions of people worldwide consume arsenic-contaminated rice; however, little is known about the uptake and bioavailability of arsenic species after arsenic-contaminated rice ingestion. OBJECTIVES: In this study, we assessed arsenic speciation in greenhouse-grown and supermarket-bought rice, and determined arsenic bioavailability in cooked rice using an in vivo swine model. RESULTS: In supermarket-bought rice, arsenic was present entirely in the inorganic form compared to greenhouse-grown rice (using irrigation water contaminated with sodium arsenate), where most (~ 86%) arsenic was present as dimethylarsinic acid (organic arsenic). Because of the low absolute bioavailability of dimethylarsinic acid and the high proportion of dimethylarsinic acid in greenhouse-grown rice, only 33 ± 3% (mean ± SD) of the total rice-bound arsenic was bioavailable. Conversely, in supermarket-bought rice cooked in water contaminated with sodium arsenate, arsenic was present entirely in the inorganic form, and bioavailability was high (89 ± 9%). CONCLUSIONS: These results indicate that arsenic bioavailability in rice is highly dependent on arsenic speciation, which in turn can vary depending on rice cultivar, arsenic in irrigation water, and the presence and nature of arsenic speciation in cooking water. Arsenic speciation and bioavailability are therefore critical parameters for reducing uncertainties when estimating exposure from the consumption of rice grown and cooked using arsenic-contaminated water

Dietary modification for women after breast cancer treatment: a narrative review

Diet is thought to account for about 25% of cancers in developed countries. It is well documented that the risks associated with both the breast cancer itself and its treatments are important for women previously treated for breast cancer. Women are at risk of recurrence of the primary disease and prone to develop treatment-induced co-morbidities, some of which are thought to be modified by diet. With a view to making dietary recommendations for the breast cancer patients we encounter in our clinical nursing research, we mined the literature to scope the most current robust evidence concerning the role of the diet in protecting women against the recurrence of breast cancer and its potential to ameliorate some of the longer-term morbidities associated with the disease. We found that the evidence about the role of the diet in breast cancer recurrence is largely inconclusive. However, drawing on international guidelines enabled us to make three definitive recommendations. Women at risk of breast cancer recurrence, or who experience co-morbidities as a result of treatment, should limit their exposure to alcohol, moderate their nutritional intake so it does not contribute to postmenopausal weight gain, and should adhere to a balanced diet. Nursing education planned for breast cancer patients about dietary issues should ideally be individually tailored, based on a good understanding of the international recommendations and the evidence underpinning the

Poly(alkyl methacrylate) tooth coatings for dental care: evaluation of the demineralisation-protection benefit using a time-resolved in vitro method

An in vitro method for the time-resolved quantification of acid-mediated tooth demineralisation has been developed and evaluated against putative non-permanent protective formulations based on a series of poly(alkyl methacrylate)s. Using a thermostatted carousel, dentally relevant substrates consisting of hydroxyapatite discs or sections of bovine teeth have been exposed to aqueous citric acid under controlled conditions, before and after being treated with the polymeric coatings. The dissolution of phosphate was monitored by the determination of 31P by Inductively Coupled Plasma—Mass Spectrometry and by the spectrophotometric phosphovanadomolybdate method. Dose-response plots constructed for both groups of treated substrates have revealed that the coatings significantly reduce erosion rates but are less effective at inhibiting tooth demineralisation than the standard fluoride treatment. The approach has enabled an evaluation of the erosion-protection efficiency of each coating

Feasibility study to assess the delivery of a novel isometric exercise intervention for people with stage 1 hypertension in the NHS: protocol for the IsoFIT-BP study including amendments to mitigate the risk of COVID-19.

BackgroundHypertension  (HTN) affects approximately 25% of the UK population and is a leading cause of mortality. Associated annual health care costs run into billions. National treatment guidance includes initial lifestyle advice, followed by anti-hypertensive medication if blood pressure (BP) remains high. However, adoption and adherence to recommended exercise guidelines, dietary advice and anti-hypertensive medication is poor. Four short bouts of isometric exercise (IE) performed 3 days per week (d/wk) at home elicits clinically significant reductions in BP in those with normal to high-normal BP. This study will determine the feasibility of delivering personalised IE to patients with stage 1 hypertension for whom lifestyle changes would be recommended before medication within NHS primary care.MethodsThis is a randomised controlled feasibility study. Participants were 18+ years, with stage 1 hypertension, not on anti-hypertensive medication and without significant medical contraindications. Trial arms will be standard lifestyle advice (control) or isometric wall squat exercise and standard lifestyle advice. Primary outcomes include the feasibility of healthcare professionals to deliver isometric exercise prescriptions in a primary care NHS setting and estimation of the variance of change in systolic BP. Secondary outcomes include accuracy of protocol delivery, execution of and adherence to protocol, recruitment rate, attrition, perception of intervention viability, cost, participant experience and accuracy of home BP. The study will last 18 months. Sample size of 100 participants (50 per arm) allows for 20% attrition and 6.5% incomplete data, based upon 74 (37 each arm) participants (two-sided 95% confidence interval, width of 1.33 and standard deviation of 4) completing 4 weeks. Ethical approval IRAS ID is 274676.DiscussionBefore the efficacy of this novel intervention to treat stage 1 hypertension can be investigated in any large randomised controlled trial, it is necessary to ascertain if it can be delivered and carried out in a NHS primary care setting. Findings could support IE viability as a prophylactic/alternative treatment option.Trial registrationISRCTN13472393 , registered 18 August 2020

A multinuclear solid state NMR, density functional theory and X-Ray diffraction study of hydrogen bonding in Group I hydrogen dibenzoates

An NMR crystallographic approach incorporating multinuclear solid state NMR (SSNMR), X-ray structure determinations and density functional theory (DFT) are used to characterise the H bonding arrangements in benzoic acid (BZA) and the corresponding Group I alkali metal hydrogen dibenzoates (HD) systems. Since the XRD data often cannot precisely confirm the proton position within the hydrogen bond, the relationship between the experimental SSNMR parameters and the ability of gauge included plane augmented wave (GIPAW) DFT to predict them becomes a powerful constraint that can assist with further structure refinement. Both the 1H and 13C MAS NMR methods provide primary descriptions of the H bonding via accurate measurements of the 1H and 13C isotropic chemical shifts, and the individual 13C chemical shift tensor elements; these are unequivocally corroborated by DFT calculations, which together accurately describe the trend of the H bonding strength as the size of the monovalent cation changes. In addition, 17O MAS and DOR NMR form a powerful combination to characterise the O environments, with the DOR technique providing highly resolved 17O NMR data which helps verify unequivocally the number of inequivalent O positions for the conventional 17O MAS NMR to process. Further multinuclear MAS and static NMR studies involving the quadrupolar 7Li, 39K, 87Rb and 133Cs nuclei, and the associated DFT calculations, provide trends and a corroboration of the H bond geometry which assist in the understanding of these arrangements. Even though the crystallographic H positions in each H bonding arrangement reported from the single crystal X-ray studies are prone to uncertainty, the good corroboration between the measured and DFT calculated chemical shift and quadrupole tensor parameters for the Group I alkali species suggest that these reported H positions are reliable

Star Formation in the Radio Galaxy NGC 4410A

The NGC4410 group of galaxies provides us a rare opportunity to study a nearby (97 h75^-1 Mpc) example of a radio galaxy (NGC4410A) embedded in an extended X-ray source, with evidence for star formation that can be readily spatially distinguished from regions dominated by the AGN and shocks. We present broadband and narrowband optical images along with optical and IUE ultraviolet spectroscopy for the radio galaxy NGC 4410A and its companion NGC 4410B. Our H-alpha+[NII] images reveal six luminous HII regions (L_H-alpha ~ 1e40 erg/s distributed in an arc near NGC 4410A. Partially completing the ring is a prominent stellar loop containing diffuse ionized gas. This filamentary gas, in contrast to the H II regions, shows spectroscopic signatures of shock ionization. The star formation in this system may have been triggered by a collision or interaction between the two galaxies, perhaps by an expanding density wave, as in classical models of ring galaxies. Alternatively, the star formation may have been induced by the impact of a radio jet on the interstellar matter. Extended Ly-alpha is detected in the ultraviolet IUE spectrum. The ultraviolet continuum, which is presumably radiated by the nucleus of NGC4410A, is not extended. NGC4410A appears to be interacting with its neighbors in the NGC4410 group, and could be an example of a spiral galaxy transforming into an elliptical.Comment: 33 pages, 9 figures. Accepted for publication in April, 2002 A

Capturing cropland and grassland management impacts on soil carbon in the UK LULUCF inventory

This project aimed to identify the extent to which emissions due to changes in Soil Organic Carbon (SOC) stocks arising from Cropland and Grassland/Grazing Land management can be incorporated into the UK’s Land Use, Land Use Change and Forestry (LULUCF) inventory. Key management activities were identified which might affect SOC stocks. A literature review carried out as part of the project concluded that tillage reduction cannot be considered a reliable management option to increase the SOC content of UK soils. However increasing crop residue returns and increasing inputs of manure and fertiliser could increase SOC stock although the SOC stock increases resulting from manure and fertiliser inputs could be outweighed by increases nitrous oxide emissions and the risk of nitrate run-off. The review found that increasing crop yields through increased fertilisation and improved crop rotation could increase the annual input of crop residues and root exudate to soils and hence increase SOC on low fertility soils. Manure additions resulted in greater C sequestration than the addition of equivalent amounts of N as mineral fertiliser and the effect lasted longer. However, increasing inputs of nitrogen from fertiliser or manure risk increasing N2O emissions which could negate any increases in SOC stock. IPCC default stock change factors were judged to be inappropriate to the UK, based on expert opinion and the literature review findings. Therefore the project used the Daily DayCent and Landscape DNDC models to attempt to estimate stock change factors for Cropland management activities under UK conditions. Although based on a very limited dataset this suggested that the effect of Cropland management activities under UK conditions might be less than implied by the IPCC stock change factors. Tillage reduction was found to have little effect on SOC stocks. Increasing manure and crop residue inputs increased SOC stocks, with manure inputs being particularly effective. A framework for reporting SOC stock changes resulting from Cropland management was developed, and used to assess mitigation options. Overall the impact of Cropland Management on SOC is likely to be very small compared to other activities in the LULUCF inventory such as land use change. The most effective mitigation option was using Cropland from annual tillage crops to perennial crops, fallow and set aside. However given the need for food production there is limited scope for such change. Increasing manure, fertiliser and crop residue inputs gave smaller increases in SOC stocks, but practical considerations limit the scope of these actions. Lack of field data on the effect of Grassland improvement on SOC stocks was identified as a knowledge gap. The literature review suggested that intensification could increase SOC stocks under pasture on mineral soils. However, expert opinion suggested that this might not be the case for rough grazing on organo-mineral soils, where intensification might lead to SOC loss. This lack of data meant that it was not possible to calibrate or validate models to estimate UK specific stock change factors for Grassland. As the IPCC stock change factors were judged to be inappropriate to UK conditions assessment of the mitigation potential of Grassland management using these factors was not carried out to avoid presenting potentially misleading results. Suggested strategies for filling these knowledge gaps are outlined in the report. Attempts to assess grass/crop rotation patterns across the UK using data from the Integrated Administration and Control System (IACS) used to handle Common Agricultural Policy (CAP) payments were hampered by difficulties in obtaining access to the data. However land use change matrices were generated for England and Wales, and used to map areas of change. Subject to data availability, this approach could be used in future inventories to give a better representation the effect of rotation patterns on SOC stocks

Priorities for mitigating greenhouse gas and ammonia emissions to meet UK policy targets

Agriculture is essential for providing food and maintaining food security while concurrently delivering multiple other ecosystem services. However, agricultural systems are generally a net source of greenhouse gases and ammonia. They, therefore, need to substantively contribute to climate change mitigation and net zero ambitions. It is widely acknowledged that there is a need to further reduce and mitigate emissions across sectors, including agriculture to address the climate emergency and emissions gap. This discussion paper outlines a collation of opinions from a range of experts within agricultural research and advisory roles following a greenhouse gas and ammonia emission mitigation workshop held in the UK in March 2022. The meeting identified the top mitigation priorities within the UK’s agricultural sector to achieve reductions in greenhouse gases and ammonia that are compatible with policy targets. In addition, experts provided an overview of what they believe are the key knowledge gaps, future opportunities and co-benefits to mitigation practices as well as indicating the potential barriers to uptake for mitigation scenarios discussed